Woman dies, police injured in 'stolen' car crash

A woman has died after a teen allegedly stole a car at gunpoint, ran a red light and slammed into other vehicles at a busy intersection.

A 16-year-old boy is in custody after the 69-year-old woman was killed and two police officers injured in the "harrowing" crash north of Brisbane on Thursday.

Queensland Premier David Crisafulli was quick to weigh in on the Murrumba Downs incident after successfully campaigning hard on youth crime measures, ending Labor's nine-year reign at the October 26 election.

"While the investigation is in its early stages, news of what has unfolded will be harrowing for Queenslanders, as it was for me," he said in a statement.

"A family is coming to terms with the loss of a loved one and the thoughts and prayers of an entire state are with them - they are owed answers."

Police allege a woman was held up at gun point and an Audi stolen by the 16-year-old at nearby Griffin, prompting officers to set up cordons in the area.

Soon afterwards the Audi was allegedly seen travelling through a Murrumba Downs intersection about 9.45am, hitting a Toyota sedan in a "high impact collision".

The Audi then hit an unmarked police vehicle at the intersection, hospitalising two officers, police said.

Chief Superintendent Adam Guild said the 69-year-old woman was trapped in the Toyota, with officers performing CPR as they waited for paramedics.

She was unable to be resuscitated.

The 16-year-old boy was taken to hospital along with the two officers. He remains under police guard at the hospital.

A search of the Audi located a firearm, Supt Guild said.

Mr Crisafulli said he would have more to say about the"heartbreaking situation" in the coming days.

"Our priority is to support the family, first responders and a community grieving an unimaginable tragedy," he said.

Mr Crisafulli's LNP government is set to usher in tough new "adult crime, adult time" legislation by Christmas after its election success.